Several laboratory studies have found that some of these bioflavonoids have anti-inflammatory and antioxidant properties. Antioxidants are substances that can override harmful molecules free radicals which are produced within your cells and which may cause tissue damage or disease. Other studies have found that it can reduce the production of specific enzymes that break down cartilage. No major side-effects have been reported in previous trials, although minor side-effects include stomach upsets and headaches.
In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. For that reason, you should be careful taking pine bark if you have hypertension or diabetes. Osteoarthritis OA is the most common form of arthritis.
It can cause joint pain and stiffness. However, until more is known, it should be used cautiously or avoided by women who are pregnant. There is not enough reliable information about the safety of taking maritime pine products if you are breast-feeding.
Stay on the safe side and avoid use. If you have one of these conditions, it's best to avoid using maritime pine.. Bleeding conditions : In theory, high doses of maritime pine might increase the risk of bleeding in people with bleeding conditions. Diabetes : In theory, high doses of maritime pine might decrease blood sugar too much in people with diabetes.
Hepatitis : In theory, taking maritime pine might worsen liver function in people with hepatitis. Surgery : Maritime pine might slow blood clotting and reduce blood sugar. There is some concern that it might cause blood sugar to go too low and increase the chance of bleeding during and after surgery. Stop using maritime pine at least 2 weeks before a scheduled surgery. Moderate Be cautious with this combination. Medications for diabetes Antidiabetes drugs Maritime pine might decrease blood sugar levels.
Diabetes medications are also used to lower blood sugar. Taking maritime pine along with diabetes medications might cause your blood sugar to be too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride Amaryl , glyburide DiaBeta, Glynase PresTab, Micronase , insulin, pioglitazone Actos , rosiglitazone Avandia , and others.
The mechanism of action is unclear. Medications that decrease the immune system Immunosuppressants Maritime pine seems to increase the immune system. By increasing the immune system, maritime pine might decrease the effectiveness of medications that decrease the immune system. Taking maritime pine along with medications that also slow clotting might increase the chances of bruising and bleeding. Some medications that slow blood clotting include aspirin, clopidogrel Plavix , dalteparin Fragmin , enoxaparin Lovenox , heparin, ticlopidine Ticlid , warfarin Coumadin , and others.
Herbs and supplements that might lower blood sugar Maritime pine might lower blood glucose levels. Using it with other herbs or supplements that have the same effect might cause blood sugar levels to drop too low.
Some herbs and supplements that can lower blood sugar include alpha-lipoic acid, chromium, devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others.
Herbs and supplements that might slow blood clotting Using maritime pine along with herbs that can slow blood clotting could increase the risk of bleeding in some people. These herbs include angelica, clove, danshen, garlic, ginger, ginkgo, Panax ginseng, and others. There are no known interactions with foods. Also, 50 mg of the same extract has been used twice daily for 6 months. Athletic performance : mg a standardized maritime pine bark extract has been used daily for months.
Poor circulation that can cause the legs to swell chronic venous insufficiency or CVI : mg of a standardized maritime pine bark extract has been taken daily in up to three divided doses for weeks. Other names.
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Cesarone, M. Improvement of signs and symptoms of chronic venous insufficiency and microangiopathy with Pycnogenol: a prospective, controlled study. Kidney flow and function in hypertension: protective effects of pycnogenol in hypertensive participants--a controlled study. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. High levels of both of these are considered risk factors for heart disease.
A review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity , diabetes , and high blood pressure.
The review found evidence that pine bark extract may:. Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties.
Pine bark extract is usually taken by mouth in capsule form. However, it can also be used topically. You can gradually increase how much you take once you get a better idea of how your body reacts to it. As a skin powder, however, you can use it safely for up to six weeks.
Work with your pediatrician to see if there are contraindications for each child. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. After taking a break for one to two weeks, they can start taking it again for several weeks. If possible, try to get pine bark extract from a local supplier, such as a health food store.
The staff there can often answer any questions you have and give you more information about specific brands. You should also do additional research or talk to your doctor before taking pine bark extract if you also take:. While pine bark extract is a natural supplement, it can have powerful effects on your health, both positive and negative. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications.
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